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Basic Science Research

Basic Science Publications: 2022-2023, Dr. Arkady Uryash and Dr. Jose Lopez.

  1. Putative malignant hyperthermia susceptibility mutation Cav1.1-R174W is insufficient to trigger a fulminant response to halothane nor confer heat stress intolerance in mice.
    Feng W, Lopez JR, Antrobus S, Zheng J, Uryash A, Dong Y, Beqollari D, Bannister R, Hopkins P, Beam KG, Allen PD, Pessah I.  (In Press J. Biol. Chem. 2023).
  2. Altered [Ca2+] regulation in cortical neurons of mice susceptible to malignant hyperthermia: An in vivo study.
    Uryash A, Adams AJ, Lopez JR. (in Press Anesthesiology. 2033)
  3. Post-isoflurane cognitive dysfunction in mice is associated with an age-related increase in neuronal intracellular calcium concentration. Cytoprotective effect of dantrolene.
    Uryash A, Mijares A, Lopez CE, Adams AJ, Allen PD, Lopez JR. (Submitted to Frontiers Aging and Neuroscience. 2023).
  4. Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance.
    Feng W, Lopez JR, Antrobus S, Zheng J, Uryash A, Dong Y, Beqollari D, Bannister RA, Hopkins PM, Beam KG, Allen PD, Pessah IN.J Biol Chem. 2023 Jun 29:104992.
  5. Smooth Muscle Cells of Dystrophic (mdx) Mice Are More Susceptible to Hypoxia; The Protective Effect of Reducing Ca2+ Influx. Uryash A, Mijares A, Estève E, Adams JA, Lopez JR.Biomedicines. 2023 Feb 19;11(2):623.
  6. Non-Invasive Pulsatile Shear Stress Modifies Endothelial Activation; A Narrative Review.
    Adams JA, Uryash A, Lopez JR.Biomedicines. 2022 Nov 28;10(12):3050.
  7. The effects of a motorized passive simulated jogging device on descent of the arterial pulse waveform dicrotic notch: A single arm placebo-controlled cross-over trial.
    Adam JA, Lopez JR, Nadkarni V, Zolkipli-Cunningham Z, Ischiropoulos H, Sackner M, Sackner M. Physiol Rep. 2022 10(15):e15418.
  8. Chronic Elevation of Skeletal Muscle [Ca2+]i Impairs Glucose Uptake. An in Vivo and in Vitro Study.
    Uryash A, Mijares A, Lopez CE, Adams JA, Lopez JR.Front Physiol. 2022 Apr 25;13:872624.
  9. The Role of the Na+/Ca2+ exchanger in the aberrant intracellular Ca2+ in cardiomyocytes of Chagas-infected rodents.
    Lopez JR, Linares N, Mijares A. Front Cell and Infect Microbiol. 2022 12:890709. 
  10. The effects of passive simulated jogging on parameters of explosive handgrip in nondiabetics and Type 2 diabetics: A single arm study.
    Adam JA, Lopez JR, Banderas V, Sackner M. Biomed Res Int. 2022 Feb 11;2022:6450844
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